Vitamin B Complex - Activated B Complex - 60 Tablets
Vegan. Gluten-Free. GMO-Free

Practitioner Quality - Not all vitamin supplements are made equal. BioNaturals supplements are formulated and developed by our Clinical Practitioners using only the best BioActive nutrients for your health and well-being.

✅ ACTIVATED FOLATE, B6 & B12 - Powerful bioavailable activated and methylated B vitamins with Methyl folate, methyl B12, Activated B6 – pyridoxal-5-phosphate. Most products on the market today use low grade forms of these B vitamins. The evidence suggests that many people cannot fully metabolise folic acid, that’s why BioNaturals products only contain activated or methyl forms of folate.

✅ PREMIUM GRADE GUARANTEE: All Our Supplements are produced in Australia. We stand behind our product with a full money back guarantee.

Best B Vitamins whats the difference - Activated and Methyl Folate vs Folic Acid. The evidence suggests that many people cannot metabolise folic acid, that’s why BioNaturals products only contain activated or methyl forms of folate, as wells as premium ingredients Activated B6 and B12.

Methyl Folate is the folate form most naturally preferred by the body, so much so that the intestinal lining has “transport proteins” that bind to it and selectively absorb it into the blood.

Activated and Methylated B Vitamins delivers biologically active forms of B vitamins: 5-MTHF folate, for example. Folic acid is a common B-vitamin supplement. Your body is supposed to convert folic acid into 5-methyltetrahydrofolate, or 5-MTHF—but not everyone has the right enzyme.

Do I really need Methyl Folate? Yes

Yes, you need it, way more than you need folic acid, because any nutrient that is closer to nature is going to be better. Clinical research has confirmed that taking methyl folate as a supplement can effectively improve the total body’s folate status.

Each tablet contains: Active Folate (Calcium folinate 216mcg Equiv Folinic acid) 200mcg; 5-Methylfolate (levomefolic acid from levomefolate calcium) 50 mcg; B12 (as Hydroxycobalamin - methyl B12) 200mcg; Vitamin B6 - Active ( Pyridoxal-5-Phosphate monhydrate) 10mg; Vitamin B1 (Thiamine nitrate) 15mg; Vitamin B2 (Riboflavin) 15mg; Vitamin B3 (Nicotinamide) 25mg; Vitamin B5 (pantothenic acid from calcium pantothenate 10.92mg) 10mg; Vitamin H (Biotin) 1.5mg.

Methyl folate vs Folic Acid

The active form of folate in the body is L-methylfolate, also known as levomefolic acid, which can cross both cell membranes and the blood-brain barrier.

Methyl Folate is the folate form most naturally preferred by the body, so much so that the intestinal lining has “transport proteins” that bind to it and selectively absorb it into the blood.

The evidence suggests that many people cannot metabolise folic acid, that’s why BioNaturals products only contain activated or methyl forms of folate, as wells as premium ingredients such as Activated B6 (pyridoxal-5-phosphate) and Activated B12 (hydroxycobalamin and methylcobalamin).

• Bioavailable and usable form of folate.
• Promotes healthy pregnancy and birth outcomes.
• Fundamental to the growth, renewal, and total functioning of our cells, tissues and organs.
• Clinically proven for healthy mood, memory and other cognitive functions, and behaviour.
• Enhances the clinically proven mood benefits of SAMe (S-adenosylmethionine).
• Essential for the brain to make the key neurotransmitters serotonin, dopamine and norepinephrine.
• Promotes the brain’s healthy production of melatonin, our major sleep hormone.

Supplement with essential nutrients like methyl-B12, methyl-folate, activated B6 (pyridoxal-5-phosphate) cod liver oil or fish oil, Vitamins C, D, E, and probiotics.  If you are double homozygous for MTHFR mutations (both your MTHFR genes are mutated), you should advance carefully with methyl-B12 and methyl folate supplementation. many people do not tolerate high doses, therefore be conservative when taking methyl forms of B vitamins.  Avoid taking high doses of niacin (vitamin B3), which can hinder methylation.

In fact, due to the potency of methyl B vitamins, as well, the small amount of folate required for optimum health, a lower daily dose is sufficient. 

Take 1 tablet per day with food, or as directed by a healthcare professional.

Warnings:

• If symptoms persist, seek the advice of a healthcare professional.
• Store below 30°C in a cool, dry place away from sunlight.
• Do not use if the seal on cap/lid has been broken.

• Animal Products
• Sulphites
• Sucralose
• Yeast
• Wheat
• Sugar
• Gluten
• Fish
• Peanuts
• Egg
• Dairy
• Any nasties
• Artificial sweeteners

Methyl Folate, B12 and B6 Pyridoxal-5-Phosphate

The evidence suggests that many people cannot metabolise folic acid, that’s why BioNaturals products only contain activated or methyl forms of folate, as wells as premium ingredients Activated B6 (P-5-P) and B12 (hydroxycobalamin or methylcobalamin).

Have you heard about the MTHFR gene mutation?

If not don't panic. 

Methyl-folate is a key player in methylation, the process of adding a methyl group to a compound. Methylation is fundamental to the proper function of almost all of the body’s systems. It’s involved in:

• Repairing and regenerating your cells, tissues and DNA
• Regulating gene expression and protein function
• Synthesizing neurotransmitters that influence mood, sleep, behaviour, cognition and memory
• Controlling homocysteine (an amino acid that can damage blood vessels)
• Keeping inflammation in check
• Assisting your liver in processing fats
• Activating and regulating the immune system
• Modifying toxins and heavy metals

Methylation is critical to our health.

Those of us with the MTHFR mutation have a defective MTHFR enzyme. We produce 30 to 70% less methyl-folate than someone without the mutation does.

 That can be bad news. With lower methylation, your performance can suffer, and you have a higher risk of developing many different diseases. But don’t fret: there are ways to increase your methylation and keep yourself running at your best. It’s a simple problem to hack, if you know about it.

Having the MTHFR mutation is an opportunity to eliminate tipping point factors that lead to disease, maximise your methylation, and optimise your diet and nutrition to change how your cells function. Your genes are one of many factors influencing your performance. You determine your future.

 Gene Mutations are Common

Each person has two copies of the MTHFR gene: one from his or her mother and one from his or her father. These are the possible genotypes of the MTHFR gene (see illustration):

• MTHFR 677 CC (two copies of C, one copy from each parent);
• MTHFR 677 CT (one copy of C from one parent, one copy of T from the other parent); or
• MTHFR 677 TT (two copies of T, one copy from each parent).

MTHFR A1298C

Do I really need Methyl Folate? Yes

Yes, you need it, way more than you need folic acid, anything close to nature is going to be better for you. Clinical research has confirmed that taking methyl folate as a supplement can effectively improve the total body’s folate status.

Crider KS, Yang TP, Berry RJ, Bailey LB. Folate and DNA methylation: A review of molecular mechanisms and the evidence for folate’s role. Adv Nutr. 2012;3(1):21-38.

 Baggott JE, Oster RA, Tamura T. Meta-analysis of cancer risk in folic acid supplementation trials. Cancer Epidemiol 2011.

Johnson MA. If high folic acid aggravates vitamin B12 deficiency what should be done about it? Nutr Rev 2007, 65:451-458.

Yang Q, Bailey L, Clarke R, et al. Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults. Am J Clin Nutr. 2012;95(5):1245-1253.